Atlas acs 2timi 51 was a doubleblind, placebocontrolled clinical trial that. Rationale and design of the antixa therapy to lower cardiovascular events in addition to standard therapy in subjects with acute coronary syndrome thrombolysis in myocardial infarction 51 atlas acs 2 timi 51 trial. Influence of modelpredicted rivaroxaban exposure and patient. An efficacy and safety study for rivaroxaban in patients with acute. Download primary results slide set pdf association of. The atlas acs 2timi 51 trial and the burden of missing data. Atlas acs2, timi 51 2012 randomized 15,342 patients with recent acs to either twicedaily doses of either 2. Rivaroxaban in patients with a recent acute coronary.
Rivaroxaban stemi study hits print as fda delivers setback. The rivaroxaban program and the management of unmet needs in. On september 6, 2012, the sponsor submitted to the fda important data related to patients who had withdrawn from the atlas acs 2 timi 51 trial as part of its complete response. Article information, pdf download for safety and efficacy of. The atlas acs 2 timi 51 trial highlights the potential impact of missing data on precluding definitive causal inferences in premarketing registration trials. Article in journal of the american college of cardiology 629 june 20 with 25 reads how we measure reads. The atlas acs 2timi 51 trial and the burden of missing data core. Investigators in the antixa therapy to lower cardiovascular events in addition to standard therapy in subjects with acute coronary syndromethrombolysis in myocardial infarction 51 atlas acs 2. E3 jacc march 12, 20 volume 61, issue 10 rivaroxaban reduces spontaneous and large myocardial infarctions. Safety and efficacy of rivaroxaban when added to aspirin. Timi 51 trial were included if they had occurred after randomization and either no later than the completion of the. The results of this analysis from the atlas acs 2timi 51 trial. The phase iii atlas acs 2timi 51 and openlabel, randomized, controlled, multicentre study. Rivaroxaban in patients with a recent acute coronary syndrome.
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